Tetrahydro curcumin - Natural

CAS: 36062-04-1

Ref. 3D-FT28087

Product Information

• Name: Tetrahydro curcumin - Natural
• Synonyms: 1,7-Bis(4-hydroxy-3-methoxyphenyl)-3,5-heptanedioneHZIV 81-2NSC 687845
• Brand: Biosynth
• Description: Tetrahydro curcumin is a natural polyphenol found in the roots of Curcuma longa. It has been shown to inhibit the activity of enzymes such as pyrazole ring hydroxylase, which is responsible for the conversion of tetrahydrocurcumin to curcumin. Tetrahydro curcumin also inhibits autophagy, which plays an important role in the development of hepatic steatosis and insulin resistance. Researchers have found that this compound can be used as a potential analytical method for detecting drug transporters. This compound also induces neuronal death and apoptosis pathway activation by inhibiting mitochondrial membrane potential and activation of caspases. Tetrahydro curcumin may also be able to prevent kidney fibrosis by preventing activation of TGF-β1 and Smad3 pathways.

Chemical properties

• Molecular weight: 372.41 g/mol
• Formula: C₂₁H₂₄O₆
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C21H24O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h5-6,9-12,24-25H,3-4,7-8,13H2,1-2H3
• InChI key: InChIKey=LBTVHXHERHESKG-UHFFFAOYSA-N
• SMILES: COc1cc(CCC(=O)CC(=O)CCc2ccc(O)c(OC)c2)ccc1O