Product Information
Name:Tolbutamide
Synonyms:
- N-[(Butylamino)carbonyl]-4-methyl-benzenesulfonamide1-Butyl-3-(p-tolylsulfonyl)urea
Brand:Biosynth
Description:Tolbutamide is a drug that is used to treat diabetes mellitus type 2. It is an inhibitor of the enzyme glucokinase and thus blocks the phosphorylation of glucose, which prevents its utilization by cells. This results in a decrease of blood glucose levels, which can be useful in the treatment of diabetes mellitus type 2. Tolbutamide has shown potent apoptosis-inducing effects on human breast cancer cells and endothelial cells. These effects are thought to be due to inhibition of protein kinase C (PKC) activity by tolbutamide. Additionally, this drug inhibits insulin secretion from pancreatic beta cells and induces cytochrome P450 enzymes, which may lead to increased metabolism of other drugs.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:270.35 g/mol
Formula:C12H18N2O3S
Purity:Min. 95%
InChI:InChI=1S/C12H18N2O3S/c1-3-4-9-13-12(15)14-18(16,17)11-7-5-10(2)6-8-11/h5-8H,3-4,9H2,1-2H3,(H2,13,14,15)
InChI key:InChIKey=JLRGJRBPOGGCBT-UHFFFAOYSA-N
SMILES:CCCCNC(=O)NS(=O)(=O)c1ccc(C)cc1
Technical inquiry about: Tolbutamide
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