Tideglusib

CAS: 865854-05-3

Ref. 3D-FT30356

Product Information

• Name: Tideglusib
• Synonyms: 4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione
• Brand: Biosynth
• Description: An irreversible GSK-3β inhibitor that reduces phosphorylation of tau proteins, protects from neuronal loss and has cognitive and behavioural benefits in murine models. Studied for its potential as a therapeutic agent in Alzheimer’s disease and other neurodegenerative diseases. Tideglusib was also shown to inhibit the main protease Mpro from the SARS-CoV-2 virus with IC50 of 1.55 μM.

Chemical properties

• Molecular weight: 334.39 g/mol
• Formula: C₁₉H₁₄N₂O₂S
• Purity: Min. 95%
• Color/Form: White To Off-White Solid