Tri-p-tolyl phosphine

CAS: 1038-95-5

Ref. 3D-FT33257

Product Information

• Name: Tri-p-tolyl phosphine
• Synonyms: Nsc 97371, Phosphine, tri-p-tolyl-, TPTP (phosphine), Tptp, Tri(4-methylphenyl)phosphine, Tri-p-tolylphosphine, Tris(4-Metilfenil)Fosfina, Tris(4-methylphenyl)phosphin, Tris(4-methylphenyl)phosphine, Tris(p-methylphenyl)phosphine, Tris(p-tolyl)phosphine

Description

Tri-p-tolyl phosphine is a coordination compound with the formula (CH3)3P. This molecule has a tetranuclear geometry, with four phosphorus atoms arranged in two square pyramids and two linear rows. The P-N bonds are strong, which leads to steric interactions that restrict rotation of the molecule. Tri-p-tolyl phosphine binds to DNA and inhibits cancer cell growth by causing DNA strand breakages. It binds to the nitrogen atoms of guanine, forming intramolecular hydrogen bonds, and also interacts with the phosphate groups of DNA. These interactions lead to inhibition of RNA synthesis and DNA replication.

• Brand: Biosynth

Chemical properties

• Molecular weight: 304.37 g/mol
• Formula: C₂₁H₂₁P
• Purity: Min. 95%
• Color/Form: White Powder
• InChI: InChI=1S/C21H21P/c1-16-4-10-19(11-5-16)22(20-12-6-17(2)7-13-20)21-14-8-18(3)9-15-21/h4-15H,1-3H3
• InChI key: InChIKey=WXAZIUYTQHYBFW-UHFFFAOYSA-N
• SMILES: Cc1ccc(P(c2ccc(C)cc2)c2ccc(C)cc2)cc1