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XAV 939
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XAV 939

CAS: 284028-89-3

Ref. 3D-FX28737

1g
2,924.00 €
2g
3,899.00 €
5g
5,141.00 €
10mg
184.00 €
50mg
538.00 €
Estimated delivery in United States, on Tuesday 10 Dec 2024

Product Information

Name:
XAV 939
Synonyms:
  • 1,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-oneNVP-XAV 939
Description:

Inhibits tankyrase (TNKS1 and TNKS2 with IC50 values of 11 and 4 nM respectively), by binding to the catalytic poly-ADP-ribose polymerase (PARP) domain. This stabilizes cytoplasmic protein Axin, mediating β-catenin depletion and thereby suppresses Wnt signalling pathway. XAV 939 has anti-proliferative and pro-apoptotic effects on neuroblastoma and colorectal cancer cells.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
312.31 g/mol
Formula:
C14H11F3N2OS
Purity:
Min. 95%
InChI:
InChI=1S/C14H11F3N2OS/c15-14(16,17)9-3-1-8(2-4-9)12-18-11-5-6-21-7-10(11)13(20)19-12/h1-4H,5-7H2,(H,18,19,20)
InChI key:
InChIKey=KLGQSVMIPOVQAX-UHFFFAOYSA-N
SMILES:
O=c1[nH]c(-c2ccc(C(F)(F)F)cc2)nc2c1CSCC2
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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