(R)-Ambrisentan

CAS: 1007358-76-0

Ref. 3D-HQB35876

Product Information

• Name: (R)-Ambrisentan
• Brand: Biosynth
• Description: (R)-Ambrisentan is an endothelin receptor antagonist, which is a pharmacological agent derived synthetically to target and inhibit specific cellular pathways. It is primarily utilized in the treatment of pulmonary arterial hypertension (PAH), where it plays a crucial role in modulating vascular function. The mode of action of (R)-Ambrisentan involves selective antagonism of the endothelin type A (ETA) receptors, which are responsible for vasoconstriction and proliferation of vascular smooth muscle cells. By blocking these receptors, it mitigates the effects of endothelin, a potent vasoconstrictor, thus reducing blood pressure and improving blood flow in pulmonary arteries.

Chemical properties

• Molecular weight: 378.40 g/mol
• Formula: C₂₂H₂₂N₂O₄
• Purity: Min. 95%