1'-Epi gemcitabine, hydrochloride

CAS: 122111-05-1

Ref. 3D-IE16542

Product Information

• Name: 1'-Epi gemcitabine, hydrochloride
• Synonyms: 4-Amino-1-(2-deoxy-2,2-difluoro-a-D-erythro-pentofuranosyl)-2(1H)-pyrimidinone, hydrochloride
• Brand: Biosynth
• Description: Gemcitabine hydrochloride is an analog of the natural nucleoside cytidine. It is a chemotherapeutic drug that is used in the treatment of pancreatic, lung and breast cancer. Gemcitabine hydrochloride is metabolized to its active form by deamination of cytosine residues in DNA. This conversion is catalyzed by the enzyme cytidine deaminase. Gemcitabine hydrochloride has been shown to be effective against metastatic pancreatic cancer and advanced-stage non-small cell lung cancer, as well as early-stage breast cancer. Gemcitabine hydrochloride has also been shown to be effective against certain types of lymphoma and leukemia.

Chemical properties

• Molecular weight: 299.66 g/mol
• Formula: C₉H₁₂ClF₂N₃O₄
• Purity: Min. 95%