Esomeprazole sodium

CAS: 161796-78-7

Ref. 3D-IM58097

Product Information

• Name: Esomeprazole sodium
• Synonyms: (S)-(-)-Omeprazole sodium 5-Methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl) methyl]sulfinyl]-1H-benzimidazole sodium salt
• Brand: Biosynth
• Description: Esomeprazole is a proton pump inhibitor used to treat gastroesophageal reflux disease and other conditions where there is too much stomach acid. It is available as a capsule or tablet in doses of 20, 40, and 60 mg. Esomeprazole inhibits the production of gastric acid by blocking the hydrogen/potassium adenosine triphosphate (H+/K+ ATPase) enzyme system at the secretory surface of the gastric parietal cells. Omeprazole is an acidic drug that blocks the H+/K+ ATPase enzyme system. The two drugs have been compared in two-way crossover studies using healthy volunteers who were given omeprazole magnesium for one week followed by esomeprazole sodium for another week. There was no difference in their effect on acid secretion or on heartburn relief. The plasma concentrations of both drugs increased with increasing dose, but there was no significant difference between them in terms of either

Chemical properties

• Molecular weight: 367.4 g/mol
• Formula: C₁₇H₁₈N₃NaO₃S
• Purity: (%) Min. 95%
• Color/Form: Powder