Pteroic acid - 60%

CAS: 119-24-4

Ref. 3D-IP35440

Product Information

• Name: Pteroic acid - 60%
• Synonyms: Folic acid impurity D4-[[2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]-benzoic acid, 4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoic acid, 4-{[(2-Amino-4-Oxo-1,4-Dihydropteridin-6-Yl)Methyl]Amino}Benzoic Acid, Benzoic acid, 4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]-, Benzoic acid, 4-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]-, Benzoic acid, p-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]-, NSC 14972, P-((2-Amino-4-Hydroxypteridin-6-Yl)Methylamino)Benzoic Acid, Pyrofolic acid, p-[(2-Amino-4-hydroxy-6-pteridylmethyl)amino]benzoic acid

Description

Pteroic acid is a synthetic compound that is an analog of the natural amino acid phenylalanine. It has been shown to inhibit protein synthesis and may be useful for the treatment of cancer. Pteroic acid can be activated by the addition of trifluoroacetic acid and reacts with metal ions such as nickel, cobalt, copper, and zinc. It also binds to receptors on tubule cells in kidney tissue. This binding inhibits the enzyme carbonic anhydrase II, which catalyzes the conversion of carbon dioxide to bicarbonate in these cells. The inhibition of this enzyme results in a decrease in bicarbonate concentration within these cells, leading to cell death.

• Brand: Biosynth

Chemical properties

• Molecular weight: 312.28 g/mol
• Formula: C₁₄H₁₂N₆O₃
• Purity: Min. 93 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C14H12N6O3/c15-14-19-11-10(12(21)20-14)18-9(6-17-11)5-16-8-3-1-7(2-4-8)13(22)23/h1-4,6,16H,5H2,(H,22,23)(H3,15,17,19,20,21)
• InChI key: InChIKey=JOAQINSXLLMRCV-UHFFFAOYSA-N
• SMILES: Nc1nc2ncc(CNc3ccc(C(=O)O)cc3)nc2c(=O)[nH]1