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Product Information
- 3-Phenyl-2,3a-diazaindene
- Imidazo[1,5-A]Pyridine, 3-Phenyl-
3-Phenylimidazo[1,5-a]pyridine is a quinoline derivative that is used as an anticancer agent. It inhibits the mitochondrial membrane potential and induces apoptosis in cancer cells. 3-Phenylimidazo[1,5-a]pyridine has also been shown to be effective against cervical cancer cells. The cytotoxic effects of this drug are not due to its DNA binding properties but may be due to its ability to inhibit the synthesis of nitroalkanes from nitrites, which may be carcinogenic. This compound binds to the ring of the quinoline moiety in active site of mitochondrial enzymes such as quinolinate phosphoribosyltransferase (QPRT). This binding prevents the enzyme from catalyzing reactions involving nucleotide biosynthesis, protein synthesis, and cell division.
Chemical properties
Technical inquiry about: 3D-KBA85446 3-Phenylimidazo[1,5-a]pyridine
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