L-Gulonic acid-1,4-lactone

CAS: 1128-23-0

Ref. 3D-MG06707

Product Information

• Name: L-Gulonic acid-1,4-lactone
• Synonyms: L-Gulonic-gamma-lactoneL-Gulonolactone, (3R,4S,5S)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxydihydrofuran-2(3H)-one (non-preferred name), (3S,4R,5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxydihydrofuran-2(3H)-one (non-preferred name), <span class="text-smallcaps">L</span>-(+)-Gulonic acid γ-lactone, <span class="text-smallcaps">L</span>-Gulono-1,4-lactone, <span class="text-smallcaps">L</span>-Gulono-γ-lactone, <span class="text-smallcaps">L</span>-Gulonolactone, Dihydroascorbic acid, Gulonic acid, γ-lactone, <span class="text-smallcaps">L</span>-, L(+)-Gulonic acid-γ-lactone, L(+)-Gulono-1,4-Lactone, L-Gulonic Gamma-Lactone, L-Gulonic-G-Lactone, L-Gulono-Gamma-Lactone, L-Gulonolactone, Reduced ascorbate, Reduced ascorbic acid, γ-Gulonolactone, L-Gulono-γ-lactone, L(+)-Gulonic Acid Gamma-Lactone, Gulonic acid, γ-lactone, L-, L-Gulonic Acid Gamma-Lactone, L-(+)-Gulonic Acid Gamma-Lactone

Description

L-Gulonic acid-1,4-lactone is an ascorbic acid derivative that inhibits the production of matrix metalloproteinases (MMPs) and other enzymes. L-Gulonic acid-1,4-lactone has been shown to inhibit the activity of MMPs in hl-60 cells, which may be due to its ability to chelate metal ions, such as zinc and copper. This molecule also has a stabilizing effect on collagen type I because it prevents cross linking between lysine amino acids. The discovery process for this molecule was found by screening clones from a cDNA library with biochemical properties similar to those of ascorbic acid. This molecule has been shown to inhibit the activation of protein kinase C (PKC) and phosphorylation of extracellular signal regulated kinase (ERK). L-Gulonic acid-1,4-lactone is metabolized through plant metabolism

• Brand: Biosynth

Chemical properties

• Molecular weight: 178.14 g/mol
• Formula: C₆H₁₀O₆
• Purity: Min. 95 Area-%
• Color/Form: White Powder