MK-0674

CAS: 887781-62-6

Ref. 3D-MKB78162

Product Information

• Name: MK-0674
• Brand: Biosynth
• Description: MK-0674 is a synthetic compound with anti-tumor activity. It targets the tumor tissue by inhibiting the production of proteins that are vital for cell division. MK-0674 has been shown to be effective in animal studies and clinical trials, but it is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex. MK-0674 has also been found to reduce the levels of collagen and nucleophilic carbonyls in cells exposed to oxidative stress, suggesting that it may have anti-oxidant properties. The drug is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid.

Chemical properties

• Molecular weight: 527.5 g/mol
• Formula: C₂₆H₂₇F₆N₃O₂
• Purity: Min. 95%