5-Bromo-2'-deoxycytidine
CAS: 1022-79-3
Ref. 3D-NB06450
| 1g | 215.00 € | ||
| 2g | 315.00 € | ||
| 5g | 538.00 € | ||
| 10g | 911.00 € | ||
| 25g | 1,607.00 € |
Product Information
- 5-Bromo-2'-deoxy-D-cytidine
- 4-amino-5-bromo-1-(2-deoxypentofuranosyl)pyrimidin-2(1H)-one
- 4-amino-5-bromo-1-[(3xi)-2-deoxy-beta-D-glycero-pentofuranosyl]pyrimidin-2(1H)-one
- 5-Bromodeoxycytidine
- Bcdr
- Brcdr
- Brn 0027385
- Bromodeoxycytidine
- C.A.S. 1,022,793
- Cytidine, 5-bromo-2'-deoxy-
- See more synonyms
- Nsc 61765
- 5-Bromo-2'-deoxycytidine
- 5-Bromo-2′-deoxycytidine
- 4-25-00-03689 (Beilstein Handbook Reference)
5-Bromo-2'-deoxycytidine is a synthetic nucleoside analogue that is used to treat diabetic neuropathy. It is structurally similar to cytidine, and inhibits the enzyme DNA polymerase by intramolecular catalysis. This causes deamination of the 5-bromo group, which prevents further synthesis of DNA. 5-Bromo-2'-deoxycytidine has been shown to be effective in vivo in a mouse model for inflammatory bowel diseases, including colitis and eosinophilic enteritis. The drug was also found to inhibit the production of Eosinophil peroxidase from HL-60 cells in vitro.
Chemical properties
Technical inquiry about: 3D-NB06450 5-Bromo-2'-deoxycytidine
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