5-Carboxy-2'-deoxyuridine

CAS: 14599-46-3

Ref. 3D-NC58344

Product Information

• Name: 5-Carboxy-2'-deoxyuridine
• Synonyms: Trifluridine related compound A
• Brand: Biosynth
• Description: 5-Carboxy-2'-deoxyuridine is a nucleoside analogue that inhibits herpes simplex virus type 1 (HSV-1) and 2 (HSV-2) replication. It is used to treat genital herpes infections caused by HSV-1 or HSV-2. 5-Carboxy-2'-deoxyuridine has been shown to inhibit the growth of human cancer cells in culture, and is currently being investigated as a potential anticancer drug. This drug binds with high affinity to the viral DNA polymerase, forming a covalent bond with the uracil base in the viral DNA chain. This prevents further elongation of the chain, inhibiting viral replication. 5-Carboxy-2'-deoxyuridine also inhibits cellular protein synthesis and cell division, which may be due to its ability to bind with aldehyde groups on surfactant proteins.END>

Chemical properties

• Molecular weight: 272.21 g/mol
• Formula: C₁₀H₁₂N₂O₇
• Purity: Min. 95%
• Color/Form: Powder