5'-Deoxy-5-fluorouridine

CAS: 3094-09-5

Ref. 3D-ND02968

Product Information

• Name: 5'-Deoxy-5-fluorouridine
• Synonyms: Doxifluridine5'dUrd, 5-fluoro-5'-deoxyuridine, 5'-DFUR, doxifluridine5'-Deoxy-5-fluoro-D-uridine5-Fluoro-5'-deoxyuridine
• Brand: Biosynth
• Description: 5'-Deoxy-5-fluorouridine (5FU) is a nucleoside that is used in the treatment of cancer. It is an antimetabolite that inhibits the synthesis of DNA, RNA, and proteins by reversibly inhibiting ribonucleotide reductase. 5FU also inhibits epidermal growth factor receptor (EGFR), which leads to apoptosis in cancerous cells. The concentration–time curve for 5FU has been determined using tissue culture and hl-60 cells as biological samples. This drug has been shown to be effective against metastatic colorectal cancer when administered with other chemotherapeutic drugs.

Chemical properties

• Molecular weight: 246.2 g/mol
• Formula: C₉H₁₁FN₂O₅
• Purity: Min. 98 Area-%
• Color/Form: White Powder