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Gemcitabine base
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Gemcitabine base

CAS: 95058-81-4

Ref. 3D-ND04237

10g
349.00 €
25g
652.00 €
50g
993.00 €
100g
1,496.00 €
250g
2,804.00 €
Estimated delivery in United States, on Friday 17 Jan 2025

Product Information

Name:
Gemcitabine base
Synonyms:
  • 2-Deoxy-2',2'-difluorocytidine4-Amino-1-[3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one2'-Deoxy-2',2'-difluor o-D-cytidine2',2'-Difluoro-2'-deoxycytidine
  • Gemcitabine
  • Cytidine, 2′-deoxy-2′,2′-difluoro-
  • LY 188011
  • DDFC
  • 2′-Deoxy-2′,2′-difluorocytidine
Description:

Gemcitabine is a prodrug that is converted to 5-fluorouracil (5FU) in the body. It has been shown to inhibit the growth of bladder and pancreatic cancer cells by interfering with the synthesis of DNA. Gemcitabine inhibits DNA replication by binding to the epidermal growth factor receptor, which leads to cell death. Gemcitabine also acts as a competitive inhibitor of deoxycytidine kinase, which prevents the formation of deoxycytidine monophosphate from deoxyuridine monophosphate, preventing DNA replication. In addition, gemcitabine can activate apoptosis in some tumor cells by increasing levels of intracellular free calcium, which leads to activation of enzymes such as phospholipases and proteases that degrade proteins, lipids, and nucleic acids.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
263.2 g/mol
Formula:
C9H11F2N3O4
Purity:
Min. 98 Area-%
Color/Form:
White Powder
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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