1-Methylpseudouridine
CAS: 13860-38-3
Ref. 3D-NM35520
1g | 1,762.00 € | ||
50mg | 238.00 € | ||
100mg | 346.00 € | ||
250mg | 542.00 € | ||
500mg | 983.00 € |
Product Information
- 1-Methyl-5-b-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione
- (1S)-1,4-anhydro-1-(1-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-D-ribitol
- 1,4-Anhydro-1-(1-Methyl-2,4-Dioxo-1,2,3,4-Tetrahydropyrimidin-5-Yl)Pentitol
- 1-Methyl-5-β-<span class="text-smallcaps">D</span>-ribofuranosyl-2,4(1H,3H)-pyrimidinedione
- 2,4(1H,3H)-Pyrimidinedione, 1-methyl-5-beta-D-ribofuranosyl-
- 2,4(1H,3H)-Pyrimidinedione, 1-methyl-5-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
- 2: PN: WO2017201317 SEQID: 2 claimed DNA
- N<sup>1</sup>-Methylpseudouridine
- Nsc 240023
- U 50228
- See more synonyms
- Uracil, 1-methyl-5-β-<span class="text-smallcaps">D</span>-ribofuranosyl-
- 1-Methyl-5-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione
- Uracil, 1-methyl-5-β-D-ribofuranosyl-
- 2,4(1H,3H)-Pyrimidinedione, 1-methyl-5-β-D-ribofuranosyl-
1-Methylpseudouridine is a substitute for uridine in modified mRNA. This substitution has shown to increase transfection by reducing immuogenicity. The 1-methylpseudouridine substituted mRNA increases protein expression due to low immune stimulation as it evades detection by the edosomal Toll-like receptor (TLR3).
Chemical properties
Technical inquiry about: 3D-NM35520 1-Methylpseudouridine
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