Product Information
- 8-Quinolinamine, N-methyl-
- 8-(Methylamino)quinoline
- Quinoline, 8-(methylamino)-
- N-Methyl-8-quinolinamine
N-Methylquinolin-8-amine (NMQ) is a cytosolic calcium ionophore, which is a drug target for the treatment of HIV infections. NMQ binds to the cytosolic calcium channels and potently inhibits the release of this ion from the cells. It also has stereoselective binding to phenyl groups and terminal alkynes. This drug has been shown to have anti-cancer properties in vitro and in vivo, as well as chemokine inhibition. The synthesis of NMQ was achieved by reacting aniline with chloroacetaldehyde followed by quinolinoyl chloride and then methylation with methyl iodide.
Chemical properties
Technical inquiry about: 3D-PAA14844 N-Methylquinolin-8-amine
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