Product Information
E 7449 is a p-glycoprotein (p-gp) substrate that inhibits the function of this transporter. It has been shown to inhibit macrophage inflammatory protein 2 in vitro, which could be due to its effects on the metabolic rate. E 7449 has also been shown to have anti-inflammatory effects in vivo and to reduce the severity of bowel disease in a rat model. This drug has also shown promising results when used as a co-therapy with platinum-based chemotherapy for solid tumours.
Chemical properties
Technical inquiry about: 3D-QVB96499 E 7449
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