Product Information
Dovitinib is a tyrosine kinase inhibitor that is used for the treatment of non-small cell lung cancer, renal cell carcinoma and other cancers. Dovitinib inhibits tumor growth by blocking the cell factor (c-KIT) and the stem cell factor receptor (c-MET). It also inhibits tumor angiogenesis through its inhibition of the colony-stimulating factor 1 receptor (CSF1R), which is involved in regulating hematopoietic stem cells. Dovitinib has been shown to inhibit tumor growth by blocking antiapoptotic genes, such as Bcl2, BclxL, Bfl-1 and Mcl-1. This drug has a terminal half-life of 15 hours.
Chemical properties
Technical inquiry about: 3D-SCB73780 Dovitinib Lactate Salt
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