Product Information
Name:Lometrexol disodium
Brand:Biosynth
Description:Lometrexol disodium is an antifolate chemotherapeutic agent, which is a synthetic derivative of the naturally occurring compound folic acid. Its mechanism of action involves the inhibition of the enzyme glycinamide ribonucleotide formyltransferase (GARFT), which plays a critical role in the de novo purine biosynthesis pathway. By targeting GARFT, Lometrexol disodium effectively disrupts nucleotide synthesis, leading to impaired DNA replication and cell division, primarily affecting rapidly proliferating cancer cells.
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Chemical properties
Molecular weight:487.4 g/mol
Formula:C21H23N5Na2O6
Purity:Min. 95%
Technical inquiry about: Lometrexol disodium
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