Product Information
- Ym 022
- 1-(3-methylphenyl)-3-{(3R)-1-[2-(2-methylphenyl)-2-oxoethyl]-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl}urea
YM022 is an orally-administered small molecule that has been shown to bind to and inhibit the activity of MMP-9, a protease that plays a key role in tumor growth. YM022 also inhibits the activity of other proteases such as gastrin, epidermal growth factor receptor (EGFR), and collagenase. It has been shown to have anti-tumor effects by inhibiting tumor growth, increasing the time of tumor cell death, and reducing the size of tumors. This drug has also been shown to inhibit the production of peptide hormones such as gastrin and histidine. YM022 is not active against cells that do not express MMP-9 or EGFR.
Chemical properties
Technical inquiry about: 3D-VFA08428 YM 022
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