YC-1

CAS: 170632-47-0

Ref. 3D-VGA63247

Product Information

• Name: YC-1
• Synonyms: 1-Benzyl-3-(5-hydroxymethyl-furan-2-yl)indazole, 1-Benzyl-3-(5-hydroxymethylfur-2-yl)indazole, 2-Furanmethanol, 5-[1-(phenylmethyl)-1H-indazol-3-yl]-, 5-[1-(Phenylmethyl)-1H-Indazol-3-Yl]-2-Furanmethanol, Lificiguat, YC 1 (pharmaceutical), Yc-1 (3-(5'-Hydroxymethyl-2'-Furyl)-1-Be Nzyl Indazole) \ Guanylyl Cyclase Acti, [5-(1-Benzyl-1H-indazol-3-yl)-furan-2-yl]-methanol, [5-(1-Benzylindazol-3-yl)furan-2-yl]methanol

Description

YC-1 is a small molecule that inhibits the activity of cyclase, an enzyme that catalyzes the conversion of ATP to cAMP. YC-1 has been shown to induce apoptosis in cancer cells by upregulating HIF-1α and decreasing intracellular Ca2+. It also inhibits the proliferation of hl-60 cells and causes significant cytotoxicity. This drug is a potential anticancer agent due to its ability to inhibit the growth of tumor cells. YC-1 can be used for treatment of oxidative injury, such as balloon injury, since it inhibits oxidative stress-induced apoptosis. It may also be effective as a treatment for α1 subunit signal pathways, which have been implicated in diseases such as Alzheimer's disease and Parkinson's disease.

• Brand: Biosynth

Chemical properties

• Molecular weight: 304.34 g/mol
• Formula: C₁₉H₁₆N₂O₂
• Purity: Min. 95%