EPZ020411 2HCl

CAS: 2070015-25-5

Ref. 3D-VHD01525

Product Information

• Name: EPZ020411 2HCl
• Brand: Biosynth
• Description: EPZ020411 2HCl is a chemical compound known as a potent selective inhibitor of the EZH2 methyltransferase, which is derived from enzymatic development processes involving high-throughput screening and medicinal chemistry optimization. With its mode of action centered on inhibiting the enzymatic activity of EZH2 (enhancer of zeste homolog 2), EPZ020411 2HCl effectively reduces the methylation of histone H3 on lysine 27 (H3K27), a critical process in gene expression regulation. This activity makes it an invaluable tool for studying epigenetic modifications and underlying oncogenic pathways.The application of EPZ020411 2HCl is predominantly in the realm of cancer research, particularly in investigating the role of EZH2 in various malignancies, including prostate, breast, and hematopoietic cancers. By targeting and inhibiting EZH2, this compound aids in elucidating mechanisms of cancer progression, potentially leading to advancements in targeted therapeutic strategies. Additionally, it serves as a pivotal reference molecule in the structural and functional studies of histone methyltransferases, contributing to our broader understanding of epigenetic regulation.

Chemical properties

• Molecular weight: 515.52 g/mol
• Formula: C₂₅H₄₀Cl₂N₄O₃
• Purity: Min. 95%