Product Information
AZ 6102 is a small molecule that inhibits histone deacetylase (HDAC) and has been shown to be effective against cancer. AZ 6102 is a potent inhibitor of HDAC1, HDAC2, and HDAC3 with IC50 values of 0.5 nM, 1.6 nM, and 8.7 nM respectively. It has been shown to induce the expression of neural genes in vitro by regulating transcriptional regulation via increased histone methylation at lysine 9 on histone H3 and trimethylation at lysine 4 on histone H4.
AZ 6102 has been shown to have an inhibitory effect on growth factor-induced proliferation of pluripotent cells derived from mouse embryos, as well as neuronal differentiation assays which are indicative of its potential use as an experimental drug for the treatment of neurodegenerative diseases such as Alzheimer's disease or Parkinson's disease.
AZ 6102 also induces cellular apoptosis
Chemical properties
Technical inquiry about: 3D-VQC28675 AZ 6102
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