Product Information
- 2-[5-Hydroxy-6,7,8,9-tetrahydro-5H-benzo[7]annulen-6-ylidene]acetic acid
- NCS 382
- Acetic acid, 2-(5,7,8,9-tetrahydro-5-hydroxy-6H-benzocyclohepten-6-ylidene)-
- 2-(5,7,8,9-Tetrahydro-5-hydroxy-6H-benzocyclohepten-6-ylidene)acetic acid
- Acetic acid, (5,7,8,9-tetrahydro-5-hydroxy-6H-benzocyclohepten-6-ylidene)-
NCS-382 is a drug that has been shown to have a variety of effects on the central nervous system. It has been shown to increase levels of gamma-aminobutyric acid (GABA) and butyric acid in the brain, which may be involved in its effects on locomotor activity and excitatory effect. NCS-382 also inhibits GABA transaminase, an enzyme that converts GABA into succinic semialdehyde, which suggests it may have an inhibitory effect on GABA. This drug also shows antagonistic properties with respect to butyric acid and excitatory amino acids such as glutamate. NCS-382 can be used for research purposes in vitro assays using homogenates of animals' brains.
Chemical properties
Technical inquiry about: 3D-VVA50501 NCS-382
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