Product Information
TAPI-1 is a potent inhibitor of the transcriptional factors EGR-1 and NF-κB. TAPI-1 inhibits the activity of these transcriptional factors by binding to their N-terminal domains. TAPI-1 also inhibits the production of cytokines such as TNF-α, IFN-γ, and IL-10 in cell culture systems. TAPI-1 has been shown to inhibit the growth of cancer cells in vitro and in vivo by inhibiting epidermal growth factor receptor (EGFR) and neurokinin 1 receptor (NKIR) signalling pathways. This drug also prevents collagen production in bronchiolitis obliterans, a disease characterized by airway obstruction due to excessive fibrosis.
Chemical properties
Technical inquiry about: 3D-WGA23571 TAPI-1
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