Product Information
JNJ-40418677 is a potent, selective, and reversible inhibitor of the aspartyl protease γ-secretase. It inhibits the cleavage of amyloid precursor protein (APP) and prevents the accumulation of β-amyloid peptide (Aβ) in the brain. JNJ-40418677 blocks Aβ production by selectively inhibiting γ-secretase activity with little or no effects on other proteases. This drug has been shown to be safe and well tolerated in early clinical trials for Alzheimer's disease.
Chemical properties
Technical inquiry about: 3D-WVB59487 JNJ-40418677
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