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BC-DXI-843
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BC-DXI-843

CAS: 2421117-98-6

Ref. 3D-WWD11798

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Estimated delivery in United States, on Monday 26 Aug 2024

Product Information

Name:
BC-DXI-843
Description:

BC-DXI-843 is a novel small molecule that inhibits the cellular apoptosis pathway by binding to the heat shock protein 70 (Hsp70) and preventing it from interacting with other proteins. BC-DXI-843 has been shown to inhibit tumorigenesis in vivo and has potential as a therapeutic agent for cancer treatment. In vitro, BC-DXI-843 inhibited cell apoptosis induced by a variety of stimuli including chemotherapy drugs, ionizing radiation, or DNA damage. This compound also reduced the expression of proapoptotic genes and increased the expression of antiapoptotic genes. The efficacy of BC-DXI-843 was evaluated using an experimental mouse model, where it showed tumor xenograft inhibition activity in both subcutaneous and orthotopic models. These results were translated into human cancer cells in vitro and in vivo, showing significant tumor xenograft inhibition activity.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
546.7 g/mol
Formula:
C28H26N4O4S2
Purity:
Min. 95%
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EINECS:
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HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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