Palbociclib dihydrochloride
CAS: 571189-11-2
Ref. 3D-WXA18911
5mg | To inquire | ||
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire | ||
100mg | To inquire |
Product Information
Palbociclib dihydrochloride is a prodrug that is metabolized to palbociclib. It is used in the treatment of breast cancer and prostate cancer. Palbociclib binds to the estrogen receptor, which prevents it from binding to DNA and activating genes. This drug also inhibits the production of estrogen, which may contribute to its antitumor effects. Palbociclib has been shown to be an effective inhibitor of mutated proteins that are responsible for tumor growth and metastasis. The crystalline form of this drug has demonstrated poor bioavailability, as well as high rates of degraders. The monohydrochloride form has demonstrated better bioavailability and decreased rates of degraders.
Chemical properties
Technical inquiry about: 3D-WXA18911 Palbociclib dihydrochloride
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