(+)-CI 1044

CAS: 197894-84-1

Ref. 3D-XHA89484

Product Information

• Name: (+)-CI 1044
• Synonyms: 3-Pyridinecarboxamide, N-(9-amino-3,4,6,7-tetrahydro-4-oxo-1-phenylpyrrolo[3,2,1-jk][1,4]benzodiazepin-3-yl)-, (R)-, 3-Pyridinecarboxamide, N-[(3R)-9-amino-3,4,6,7-tetrahydro-4-oxo-1-phenylpyrrolo[3,2,1-jk][1,4]benzodiazepin-3-yl]-, Ci-1044, N-[(3R)-9-Amino-3,4,6,7-tetrahydro-4-oxo-1-phenylpyrrolo[3,2,1-jk][1,4]benzodiazepin-3-yl]-3-pyridinecarboxamide, Pd-189659
• CAS: 197894-84-1

Description

(+)-CI 1044 is a peptide that has been shown to activate the G-protein coupled receptor, GlyR. This activation leads to increased levels of intracellular calcium and neurotransmitter release. (+)-CI 1044 is a potent inhibitor of ion channels, especially voltage-gated potassium channels. It also inhibits the activity of peptides that bind to glycine receptors in the central nervous system. The binding site of (+)-CI 1044 is located at the N-terminal segment of the GlyR. The binding site for (+)-CI 1044 has been identified with an antibody by immunoprecipitation and Western blot analysis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 397.4 g/mol
• Formula: C₂₃H₁₉N₅O₂
• Purity: Min. 95%