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2-Methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl dihydrogen phosphate
CAS: 222030-63-9
Ref. 3D-XIA03063
| 1g | To inquire |
Product Information
- Fosbretabulin
- Combretastatin A4 phosphate
- Phenol, 2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-, 1-(dihydrogen phosphate)
- Combretastatin A-4P
- Phenol, 2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]-, dihydrogen phosphate
2-Methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl dihydrogen phosphate is a synthetic compound that is structurally related to combretastatin A-4. It has been shown to inhibit the proliferation of HL60 cells and induce apoptosis in these cells by inhibiting tubulin polymerization. 2-Methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl dihydrogen phosphate has also been shown to bind to DNA and other cellular components such as lipids and proteins. This binding prevents the formation of dsDNA breaks during intercalation of this agent with DNA. 2-Methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl dihydrogen phosphate has potential anticancer activity due to its ability to inhibit the growth of
Chemical properties
Technical inquiry about: 3D-XIA03063 2-Methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl dihydrogen phosphate
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