Product Information
ZJ 43 is a peptide with high purity and ion channels. ZJ 43 was discovered from the venom of the Chinese scorpion (Heterometrus longimanus). It is an activator of various ion channels, such as human Kv1.2 channel, rat Kv4.3 channel, and insect Mg2+ channel. The activation of these channels can inhibit the generation of action potentials in neurons and muscles cells. In addition, ZJ 43 can also activate the receptor Ligand in mammalian cells to increase the production of intracellular cAMP, which may be related to its pharmacological effects on cellular activities.
ZJ 43 has been shown to inhibit protein interactions by binding to the ligand-binding domain on the receptor and blocking access to other proteins that interact with it.
Chemical properties
Technical inquiry about: 3D-YDB33120 ZJ 43
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