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USL311
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USL311

CAS: 1373268-67-7

Ref. 3D-YEC26867

10mgTo inquire
100mgTo inquire
Estimated delivery in United States, on Thursday 16 Jan 2025

Product Information

Name:
USL311
Description:

USL311 is a synthetic small molecule that acts as an inhibitor of the ion channel TRPV4. It is also a potent activator of the G protein-coupled receptor GPR81, which may play a role in the regulation of insulin secretion. USL311 binds to the TRPV4 channel and prevents the influx of calcium ions into cells. This inhibition can be reversed by increasing concentrations of extracellular calcium ions. USL311 has shown no effect on other TRPV channels, such as TRPV1 or TRPV2, or on other receptors.
TRPV4 is expressed in a number of tissues including vascular smooth muscle cells and airway epithelial cells. The activation of GPR81 by USL311 may regulate insulin secretion and glucose homeostasis in pancreatic beta cells by inhibiting the release of glucagon from alpha cells and stimulating insulin release from beta cells.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
422.57 g/mol
Formula:
C24H34N6O
Purity:
Min. 95%
MDL:
Melting point:
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Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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