Product Information
GR 125743 is an inhibitor of the receptor tyrosine kinases, a group of signaling proteins that are involved in many cellular processes. GR 125743 specifically inhibits the activity of the epidermal growth factor receptor (EGFR) and has been shown to be effective in inhibiting tumor cell proliferation and migration. GR 125743 also binds to the extracellular domain of the EGFR, which prevents it from binding to its ligands. This inhibition is dependent on the presence of extracellular calcium ions. GR 125743 has been shown to have no effect on ion channels or other protein interactions.
Chemical properties
Technical inquiry about: 3D-YFA54733 GR 125743
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