Product Information
PF 05105679 is a novel small molecule that acts as a selective antagonist of the neuropeptide receptor, P2X7. PF 05105679 has been shown to inhibit the activation of this receptor. It has also been shown to inhibit ATP-induced ion currents in excitable cells and to block ATP-induced P2X7 receptor-mediated responses in neutrophils and macrophages. PF 05105679 is an inhibitor of the P2X7 receptor, which may provide a new therapeutic target for inflammatory diseases such as rheumatoid arthritis.
Chemical properties
Technical inquiry about: 3D-YFC58331 PF 05105679
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