Product Information
- (E)-4-(2-(2-(N-(4-Methoxybenzenesulfonyl)amino)phenyl)ethenyl)pyridine
- Benzenesulfonamide, 4-methoxy-N-(2-((1E)-2-(4-pyridinyl)ethenyl)phenyl)-
- Benzenesulfonamide, 4-methoxy-N-(2-(2-(4-pyridinyl)ethenyl)phenyl)-, (E)-
HMN-154 is a potent, selective and orally bioavailable small molecule antagonist of the potassium channel Kv1.2 that blocks the channel in a voltage-dependent manner and inhibits action potentials. HMN-154 was developed as a research tool to study Kv1.2 function in cells and tissues, but has also been used as an inhibitor of human Kv1.2 channels in vitro and in vivo. HMN-154 is also being investigated for its effects on other ion channels such as Kv4.3 and Kv4.1, which are expressed in neurons and may play a role in epilepsy or schizophrenia, respectively.
Chemical properties
Technical inquiry about: 3D-YGA52892 HMN-154
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