Product Information
- 1,7-Heptanediamine, N1,N7-bis(1,2,3,4-tetrahydro-9-acridinyl)-, hydrochloride (1:2)
- 1,7-Heptanediamine, N,N′-bis(1,2,3,4-tetrahydro-9-acridinyl)-, dihydrochloride
Bis(7)-tacrine is a neuroprotective drug that has been shown to prevent glutamate-induced excitotoxicity in the cerebellum. It binds to the noncompetitive NMDA receptor and inhibits calcium ion flux into the cell, thereby reducing neuronal death. The mechanism of action for Bis(7)-tacrine is similar to that of other neuroprotective drugs, such as memantine or riluzole. In addition, Bis(7)-tacrine has also been found to be a potent inhibitor of acetylcholinesterase activity. This may be due to its ability to inhibit the formation of reactive oxygen species (ROS) and nitric oxide (NO).
Chemical properties
Technical inquiry about: 3D-ZIA44512 Bis(7)-tacrine
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