Ps-1145 dihydrochloride

CAS: 1049743-58-9

Ref. 3D-ZRB74358

Product Information

• Name: Ps-1145 dihydrochloride
• Brand: Biosynth
• Description: PS-1145 dihydrochloride is a synthetic chemical compound that acts as a selective inhibitor of the enzyme IκB kinase β (IKK-β). This compound is typically derived through complex chemical synthesis techniques in laboratory environments. PS-1145 targets the NF-κB signaling pathway by directly binding to IKK-β, thereby inhibiting its activity. This inhibition prevents the phosphorylation and subsequent degradation of IκB proteins, which in turn retains NF-κB in the cytoplasm and prevents its transcriptional activity in the nucleus.

Chemical properties

• Molecular weight: 395.7 g/mol
• Formula: C₁₇H₁₃Cl₃N₄O
• Purity: Min. 95%