Product Information
NPBA is a potent and selective antagonist of the nicotinic acetylcholine receptor. The binding site of NPBA is on the alpha subunit, which has a high affinity for nicotine. NPBA binds to the receptor with an IC50 of 10 nM and blocks activation by endogenous or exogenous nicotine with an IC50 of 1 nM. It can be used as a research tool to study the function of nicotinic acetylcholine receptors in various cells, such as neurons, muscle cells, and cancer cells.
NPBA also inhibits protein synthesis in bacteria and other microorganisms.
Chemical properties
Technical inquiry about: 3D-ZVA03340 Npba
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