41-Y0001329 - atorvastatin-impurity-b-crs

<p>Orally active atorvastatin inhibits HMG-CoA reductase, lowers lipids, hinders SV-SMC cell growth, and can up thrombotic risk with clopidogrel.</p>

<p>Atorvastatin is a statin used to reduce low-density lipoprotein (LDL) cholesterol and triglyceride levels in the blood. It is marketed under the trade name Lipitor®. Atorvastatin inhibits the enzyme HMG-CoA reductase, which is responsible for the production of cholesterol. This drug also reduces plaque formation in atherosclerotic lesions by inhibiting inflammation and has been shown to be effective in reducing mortality from coronary heart disease. In addition, atorvastatin has a low incidence of side effects, particularly when compared with other statins such as simvastatin, pravastatin, or lovastatin. The risk of developing adverse reactions to this drug increases with age and prolonged use. The most common side effects are muscle pain or weakness, headache, nausea, high blood sugar levels (elevated glucose), and liver problems.</p>

<p>ATORVASTATIN FOR PEAK IDENTIFICATION B CRS</p>

<p>ATORVASTATIN IMPURITY MIXTURE CRS</p>

<p>ATORVASTATIN CALCIUM CRS</p>

<p>ATORVASTATIN FOR PEAK IDENTIFICATION A CRS</p>

<p>ATORVASTATIN FOR PEAK IDENTIFICATION C CRS</p>

Atorvastatin calcium

Atorvastatin impurity

Cardiovascular drugs, nesoi

<p>Drugs with nitrogen hetero-atom(s) only, aromatic or modified aromatic, nesoi</p>

Heterocyclic compounds with nitrogen hetero-atom(s) only, aromatic or modified aromatic, nesoi

Aromatic or modified aromatic heterocyclic compounds withnitrogen hetero-atom(s) only nesoi

<p>Aromatic cyclic amides (including cyclic carbamates) and their derivatives; salts thereof</p>