AC-46249 - nebivolol-hydrochloride | 152520-56-4
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Nebivolol Hydrochloride
CAS:Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoiFormula:C22H25F2NO4·HClColor and Shape:White Off-White PowderMolecular weight:441.15184Nebivolol Hydrochloride
CAS:Formula:C22H26ClF2NO4Purity:97%Color and Shape:SolidMolecular weight:441.8959Nebivolol hydrochloride
CAS:Nebivolol hydrochloride is a beta-1 blocker and vasodilator treating hypertension and heart failure in the elderly.Formula:C22H25F2NO4·HClPurity:99.77% - >99.99%Color and Shape:White To Off-White PowderMolecular weight:441.90Nebivolol hydrochloride
CAS:Formula:C22H25F2NO4·HClPurity:≥ 98.0% (anhydrous basis)Color and Shape:White to off-white crystalline powderMolecular weight:441.90Nebivolol Hydrochloride
CAS:Formula:C22H25F2NO4·HClPurity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:441.90Nebivolol Hydrochloride
CAS:Controlled ProductFormula:C22H25F2NO4·ClHColor and Shape:NeatMolecular weight:441.90Nebivolol Hydrochloride
CAS:<p>Applications Nebivolol Hydrochloride is a highly selective β1-adrenoceptor antagonist.<br>References Van de Water, A., et al.: J. Cardiovasc. Pharmacol., 11, 552 (1988), De Cree, J., et al.: Angiology, 41, 95 (1990);<br></p>Formula:C22H25F2NO4·ClHColor and Shape:WhiteMolecular weight:441.90Nebivolol hydrochloride
CAS:Controlled ProductNebivolol HCl is a beta-blocker that is used to treat high blood pressure and heart failure. It is a prodrug that is metabolized in vivo to its active form, nebivolol. Nebivolol HCl has a low bioavailability of about 5%, which may be due to the presence of excipients or the formation of solid dispersions with other ingredients in the formulation. Nebivolol HCl also interacts with many drugs that are metabolized by CYP2D6, CYP3A4, and CYP1A2 enzymes, such as metoprolol succinate, sodium citrate, and hydrochloric acid. This drug also has an adverse effect on geriatric patients because it can cause dizziness due to orthostatic hypotension.Formula:C22H25F2NO4•HClPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:441.9 g/mol
