Product Information
- Phenylbiguanide hydrochloride
Compound PDK0269, as 5-HT3 receptor agonists(3-100 μM, pEC50 5.05±0.06), acutely increased XII (hypoglossal) burst frequency and regularity, and decreased bursts/episode . Phenylbiguanide produced a dose-related (10-500 microM) increase in the release of dopamine (280-2000%). When nomifensine (5 microM) was included in the Ringer solution, the effect of Compound PDK0269 on the release of dopamine was ameliorated or inhibited.
Chemical properties
Technical inquiry about: TM-PDK0269 1-Phenylbiguanide HCl
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