Trichlormethiazide

CAS: 133-67-5

Ref. TM-T0114

Product Information

• Name: Trichlormethiazide
• Synonyms: Naqua, Metahydrin, Trichlormetazid, 3-Dichloromethyl-6-chloro-7-sulfamoyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide, 3-Dichloromethyl-6-chloro-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide, 3-Dichloromethylhydrochlorothiazide, 6-Chloro-3-(dichloromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 6-Chloro-3-(dichloromethyl)-3,4-dihydro-7-sulfamyl-1,2,4-benzothiadiazine-1,1-dioxide, 6-Chloro-3-dichloromethyl-3, 4-dihydro-2H-1, 2, 4-benzothiadiazine-7-sulfonamide-1, 1-dioxide, 6-Chloro-3-dichloromethyl-3,4-dihydro-7-sulfamoyl-2H-1,2,4-benzothiadiazine 1,1-dioxide, Achletin, Anatran, Anistadin, Aponorin, Carvacron, Ciba 7057-Su, Diurazida, Diurese, Diuroral, Esmarin, Fluitran, Flurese, Flutra, Gangesol, Hydrotrichlorothiazide, Intromene, Kubacron, Metahydrin, Metatensin, Nakva, Naqua, Naquasone, Naquival, Nsc 61560, Salirom, Tachionin, Tolcasone, Trichlormetazid, Trichlormethiazid, Trichloromethiazide, Triclormetiazida, Triflumen
• CAS: 133-67-5

Description

Trichlormethiazide (Naqua) is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics. Trichlormethiazide appears to block the active reabsorption of chloride and possibly sodium in the ascending loop of Henle, altering electrolyte transfer in the proximal tubule.

• Brand: Targetmol

Chemical properties

• Molecular weight: 380.66
• Formula: C₈H₈Cl₃N₃O₄S₂
• Purity: 99.54%
• Color/Form: Solid
• InChI: InChI=1S/C8H8Cl3N3O4S2/c9-3-1-4-6(2-5(3)19(12,15)16)20(17,18)14-8(13-4)7(10)11/h1-2,7-8,13-14H,(H2,12,15,16)
• InChI key: InChIKey=LMJSLTNSBFUCMU-UHFFFAOYSA-N
• SMILES: NS(=O)(=O)c1cc2c(cc1Cl)NC(C(Cl)Cl)NS2(=O)=O