Roflumilast
CAS: 162401-32-3
Ref. TM-T1024
5mg | 59.00 € | ||
10mg | 77.00 € | ||
25mg | 120.00 € | ||
50mg | 182.00 € | ||
100mg | 252.00 € | ||
1ml*10 (DMSO) | 63.00 € |
Product Information
- B9302-107, BYK 20869, APTA 2217, BY 217
- 3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide
- 3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide
- Arq 151
- B 9302-107
- Benzamide, 3-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)-
- By 217
- Byk 20869
- Daliresp
- Daxas
- See more synonyms
- Libertek
- N-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide
Roflumilast (APTA 2217) is an orally available, long-acting inhibitor of phosphodiesterase (PDE) type 4 (PDE4), with anti-inflammatory and potential antineoplastic activities. Upon administration, roflumilast and its active metabolite roflumilast N-oxide selectively and competitively bind to and inhibit PDE4, which leads to an increase of both intracellular levels of cyclic-3', 5'-adenosine monophosphate (cAMP) and cAMP-mediated signaling.
Chemical properties
Technical inquiry about: TM-T1024 Roflumilast
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