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Roflumilast
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Roflumilast

CAS: 162401-32-3

Ref. TM-T1024

5mg
59.00 €
10mg
77.00 €
25mg
120.00 €
50mg
182.00 €
100mg
252.00 €
1ml*10 (DMSO)
63.00 €
Estimated delivery in United States, on Friday 17 May 2024

Product Information

Name:
Roflumilast
Synonyms:
  • B9302-107, BYK 20869, APTA 2217, BY 217
  • 3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide
  • 3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide
  • Arq 151
  • B 9302-107
  • Benzamide, 3-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)-
  • By 217
  • Byk 20869
  • Daliresp
  • Daxas
  • See more synonyms
  • Libertek
  • N-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide
Description:

Roflumilast (APTA 2217) is an orally available, long-acting inhibitor of phosphodiesterase (PDE) type 4 (PDE4), with anti-inflammatory and potential antineoplastic activities. Upon administration, roflumilast and its active metabolite roflumilast N-oxide selectively and competitively bind to and inhibit PDE4, which leads to an increase of both intracellular levels of cyclic-3', 5'-adenosine monophosphate (cAMP) and cAMP-mediated signaling.

Brand:
Targetmol
Long term storage:
Notes:

Chemical properties

Molecular weight:
403.21
Formula:
C17H14Cl2F2N2O3
Purity:
100.00%
Color/Form:
Solid
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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