Estimated delivery in United States, on Thursday 8 Aug 2024
Product Information
Name:
BACE1-IN-5
Synonyms:
- BACE1IN5
- BACE-1-IN-5
CAS:
Description:
BACE1-IN-5 (Compound 15), a potent β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, demonstrates significant efficacy with an IC50 of 9.1 nM for BACE1 inhibition and an impressive IC50 of 0.82 nM against cellular amyloid-β (Aβ) production. Additionally, it is engineered to enhance hERG inhibition and P-gp efflux, indicating its optimized medicinal chemistry profile [1].
Brand:
Targetmol
Long term storage:
Notes:
Chemical properties
Molecular weight:
461.41
Formula:
C18H16F5N5O2S
Purity:
98%
Color/Form:
Solid
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TM-T10453 BACE1-IN-5
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