BACE
BACE inhibitors are compounds that target the Beta-Site Amyloid Precursor Protein Cleaving Enzyme (BACE), which is crucial for the production of beta-amyloid, a protein associated with the formation of amyloid plaques in Alzheimer's disease. By inhibiting BACE, these compounds aim to reduce the production of beta-amyloid and its accumulation in the brain, potentially slowing the progression of Alzheimer's disease. BACE inhibitors are a major focus in the development of therapeutic strategies for neurodegenerative diseases. At CymitQuimica, we offer BACE inhibitors to support your research in Alzheimer's disease, amyloid biology, and neurodegeneration.
Found 35 products for "BACE".
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Elenbecestat
CAS:Elenbecestat (E2609) is an effective oral bioutilization and CNS penetrating ACE-1 inhibitor for the treatment of Alzheimer's disease.Formula:C19H18F3N5O2SPurity:99.95%Color and Shape:White SolidMolecular weight:437.439BACE1-IN-4
CAS:BACE1-IN-4 is a selective BACE1 inhibitor with nanomolar activity and significantly weaker BACE2 inhibition, and can be used for research on amyloid precursor protein secretase biology and Alzheimer's disease-related drug discovery.Formula:C21H23F2N5O4S2Purity:99.66%Color and Shape:SolidMolecular weight:511.57Anti-BACE1 Antibody-FITC (8D358)
Anti-BACE1 Antibody-FITC (8D358) is a FITC-conjugated Rabbit antibody targeting BACE1. Anti-BACE1 Antibody-FITC (8D358) can be used in FCM.Color and Shape:Odour LiquidAnti-BACE1 Antibody-PE (8D358)
Anti-BACE1 Antibody-PE (8D358) is a PE-conjugated Rabbit antibody targeting BACE1. Anti-BACE1 Antibody-PE (8D358) can be used in FCM.Color and Shape:Odour LiquidAnti-BACE1 Antibody (2J206)
Anti-BACE1 Antibody (2J206) is an antibody targeting BACE1. Anti-BACE1 Antibody (2J206) can be used in ELISA, WB.Color and Shape:Odour LiquidAnti-BACE1 Antibody (3R945)
Anti-BACE1 Antibody (3R945) is a Mouse antibody targeting BACE1. Anti-BACE1 Antibody (3R945) can be used in ELISA.Color and Shape:Odour LiquidAnti-BACE1 Antibody (8D358)
Anti-BACE1 Antibody (8D358) is a Rabbit antibody targeting BACE1. Anti-BACE1 Antibody (8D358) can be used in FCM,ICC/IF.Color and Shape:Odour LiquidBACE1 Protein, Human, Recombinant (His)
BACE1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Purity:> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC - > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLCColor and Shape:Lyophilized PowderMolecular weight:49.5 kDa (predicted); 55-70 kDa (reducing condition, due to glycosylation)BACE1 Protein, Human, Recombinant (hFc)
BACE1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Color and Shape:Lyophilized PowderMolecular weight:75.2 kDa (predicted, pro-form); 72.6 kDa (predicted, mature-form); 85-100 kDa (reducing condition, due to glycosylation)BACE1 Protein, Human, Recombinant
BACE1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 49 kDa and the accession number is A0A024R3D7.Color and Shape:Lyophilized PowderMolecular weight:49 kDa (predicted); 65 kDa (reducing condition, due to glycosylation)Tenuifolin
CAS:Tenuifolin has no inherent toxicity to either the transfected or wild type cells at the effective concentrations, it inhibits amyloid-β secretion in vitro.Formula:C36H56O12Purity:98.71% - 99.90%Color and Shape:Yellow SolidMolecular weight:680.8226Epiberberine
CAS:1.Formula:C20H18NO4Purity:98.52% - 99.59%Color and Shape:SolidMolecular weight:336.36LY2886721
CAS:LY2886721, a BACE inhibitor, is used for the therapy of Alzheimer's Disease.Formula:C18H16F2N4O2SPurity:99% - 99.75%Color and Shape:SolidMolecular weight:390.407Aloenin
CAS:1. Aloenin (Aloenin A) and aloe-emodin are active principles for inhibition of c-ADH and c-ALDH activities in vitro.Formula:C19H22O10Purity:99.42% - 99.69%Color and Shape:SolidMolecular weight:410.372Scoulerine
CAS:Scoulerine is an inhibitor of ß-site amyloid precursor protein cleaving enzyme 1(BACE1).Formula:C19H21NO4Purity:98.62% - 99.64%Color and Shape:White SolidMolecular weight:327.3743Eslicarbazepine Acetate
CAS:Eslicarbazepine Acetate (Zebinix) is an anticonvulsant medication approved for use as an adjunctive therapy for partial-onset seizures.Formula:C17H16N2O3Purity:99.58% - >99.99%Color and Shape:White SolidMolecular weight:296.32Aloeresin D
CAS:Aloeresin D, a natural chromone glycoside, inhibits β-Secretase (BACE1) activity (IC50: 39 μM).Formula:C29H32O11Purity:98.11% - 99.57%Color and Shape:SolidMolecular weight:556.5578Verubecestat
CAS:Verubecestat (MK-8931) (MK-8931) is an effective and specific β-secretase inhibitor and β-site APP-cleaving enzyme 1 inhibitor or BACE1 protein inhibitor.Formula:C17H17F2N5O3SPurity:94.64% - 99.55%Color and Shape:SolidMolecular weight:409.41LY2811376
CAS:LY2811376, an orally available non-peptidic β-secretase(BACE1) inhibitor (IC50: 239-249 nM), can decrease Aβ secretion (EC50: 300 nM).Formula:C15H14F2N4SPurity:97.92% - 99%Color and Shape:SolidMolecular weight:320.36BACE-IN-1 acetate
BACE-IN-1 acetate (350228-37-4), a BACE1 inhibitor with three disulfide bonds and N-linked glycosylation, is used in assays.Formula:C75H122N16O29Purity:99.71%Color and Shape:SolidMolecular weight:1711.86
