AMG 511
CAS: 1253573-53-3
Ref. TM-T14214
1mg | 91.00 € | ||
2mg | 106.00 € | ||
5mg | 150.00 € | ||
10mg | To inquire | ||
50mg | To inquire | ||
1ml*10 (DMSO) | 278.00 € |
Product Information
AMG 511 is a potent and orally available pan inhibitor of class I PI3Ks(Kis of 4 nM, 6 nM, 2 nM and 1 nM for PI3Kα, β, δ and γ, respectively). It exhibits anti-tumor activity in mouse glioblastoma xenograft model[1]. AMG 511 significantly suppresses PI3K signaling that is indicated by p-Akt (Ser473) decrease.
Chemical properties
Technical inquiry about: TM-T14214 AMG 511
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