Product Information
Name:MRT-92
Brand:Targetmol
Description:MRT-92 is an antagonist of Smoothened (Smo) with anti-cancer activity, featuring a binding affinity (Ki) of 0.7 nM. It inhibits the Hedgehog signaling pathway by obstructing the overlapping binding sites within the transmembrane domain of the Smoothened receptor and suppresses the proliferation of cerebellar granule cells in rodents (IC50=0.4 nM). MRT-92 is utilized for research into cerebellar gliomas.
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Chemical properties
Molecular weight:566.65
Formula:C33H34N4O5
Color/Form:Solid
Technical inquiry about: MRT-92
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