Product Information
Name:AJI-100
Brand:Targetmol
Description:AJI-100 serves as a dual-target inhibitor, effectively blocking Aurora kinase A and JAK2, with respective IC50 values of 12.7 nM and 18.5 nM. It inhibits T cell mitosis and cell polarity by directly targeting Aurora kinase A and reduces STAT3 phosphorylation by inhibiting JAK2 activation, consequently diminishing the differentiation of TH1 and TH17 cells. This compound is utilized in researching immune response regulation and the prevention of graft-versus-host disease (GVHD).
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:323.32
Formula:C17H14FN5O
Color/Form:Solid
Technical inquiry about: AJI-100
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